Covid-19 vaccine: four years later, the list of persistent symptoms is growing

Bell’s palsy (facial nerve palsy)

What: Sudden facial weakness on one side.

Which vaccines: Small signal noted in early mRNA vaccine trials and some surveillance, though causal link uncertain.

How common: Very rare; most cases recover. PMC

Transverse myelitis / other spinal cord inflammation

What: Inflammation of the spinal cord causing weakness, sensory changes.

Which vaccines: Reported as single cases/rare clusters in early surveillance; signal is low and investigations continue.

How common: Extremely rare. Taylor & Francis Online

Arrhythmias and palpitations (non-myocarditis cardiac events)

10. Arrhythmias and palpitations (non-myocarditis cardiac events)

What: Heart rhythm disturbances post-vaccination sometimes reported; many are benign and transient.

Which vaccines: Reported across types in surveillance data.

How common: Uncommon; often self-limited and investigated to rule out myocarditis. PubMed

Multisystem inflammatory syndrome (MIS)-like presentations

What: Hyperinflammatory syndrome (more commonly reported after infection, rare after vaccination).

Which vaccines: Mostly linked to SARS-CoV-2 infection; very rare vaccine-associated reports exist and are investigated.

How common: Extremely rare. PMC

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